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    搜索結果包含 synthesize 的內容

    Jul 10,2025
    TBN是一種治療缺血性卒中的新型臨床候選藥物，本研究中TBN通過尊龍凱時合成
    TBN (purity 99.3%) used in this study was synthesized by Medicilon.
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    Jul 10,2025
    跨膜結構域寡聚體的結構測定新方法，其中TriNTA通過尊龍凱時合成
    TriNTA was synthesized by Medicilon.
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    Jul 03,2025
    特異性RET抑制劑CPT可改善阿爾茨海默病，本研究中CPT由尊龍凱時化學部門合成
    The compound was synthesized for Cerepeut Inc. by the Chemistry Branch of Medicilon.
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    Jul 02,2025
    口服IRAK4抑制劑可預防急性呼吸窘迫綜合征，本研究中抑制劑通過尊龍凱時合成
    BAY-1834845 and PF-06650833 are synthesize by Medicilon.
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    Jun 12,2025
    通過增強MTUS1穩定性抑制透明細胞腎細胞癌轉移，本研究中體外實驗重組蛋白通過尊龍凱時合成和純化
    Recombinant proteins were synthesized and purified by Medicilon
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    Jun 11,2025
    丁烯酸內酯是一種很有前景的天然防污產品，本研究中純度>99%的丁烯酸內酯通過尊龍凱時合成
    Butenolide with a purity >99% was synthesized by Medicilon.
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    99%的丁烯酸內酯通過尊龍凱時合成">
    Jul 17,2023
    AP39是一種新合成的線粒體靶向的H2S供體，本研究中AP39通過尊龍凱時設計和合成
    Alzheimer's disease (AD) is the most universal age-related neurodegenerative disease. AP39 is a newly synthesized mitochondrially targeted H2S donor on mitochondrial function. AP39 increases intra
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    Jul 05,2023
    研究人員設計并合成了一種光籠PI3K抑制劑1，它可以通過紫外線照射激活，釋放出高效PI3K抑制劑2。化合物1和2的ADME研究通過尊龍凱時進行
    Aberrant activation of the PI3K pathway has been intensively targeted for cancer therapeutics for decades.? In this work, researchers designed and synthesized a novel photocaged PI3K inhibitor 1,
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    Jun 28,2023
    SAHA可有效恢復阿爾茨海默病模型的記憶能力，本研究中SAHA通過尊龍凱時合成
    SAHA was synthesized by Medicilon and was given to mice as 50?mg/kg doses. Injections (10?mL/kg) were given intraperitoneally and were alternated daily between left and right sides of the abdomen. Chronic treatments of SAHA completely restored performance
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    Jun 28,2023
    設計合成一系列DHODH抑制劑作為潛在的類風濕性關節炎治療藥物，本研究中PK實驗通過尊龍凱時進行
    Human dihydroorotate dehydrogenase (DHODH) is a viable target for the development of therapeutics to treat cancer and immunological diseases. Herein, researchers designed and synthesized a series of acrylamide-based novel DHODH inhibitors as potential rhe
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    Jun 28,2023
    開發并驗證新的LC-MS/MS方法，用于定量人血漿中達拉非尼及其主要代謝物羥基達拉非尼 (OHD)。本研究中OHD(純度>99%)通過尊龍凱時合成
    OHD (purity >99 %) was synthesized by Medicilon. Medicilon synthetic chemistry team is capable of the independent design of synthesis pathways and complex compound treatments, key to helping accelerate drug discovery.
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    99%)通過尊龍凱時合成">
    Jun 28,2023
    GS-5801是一種高效KDM5抑制劑，具有抗HBV活性，本研究中GS-5801通過尊龍凱時合成
    GS-5801, a potent inhibitor of KDM5, has antiviral activity against HBV in a primary human hepatocytes infection model, with the cellular permeability, oral bioavailability. GS-5801 was synthesized by Medicilon.
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    Jun 28,2023
    設計合成一種新型選擇性的口服有效蘇氨酸酪氨酸激酶 (TTK) 抑制劑，PK研究均通過尊龍凱時進行
    TTK inhibition is an attractive wide-spectrum strategy for cancer therapy. Researchers designed and synthesized a series of pyrido[2, 3-d]pyrimidin-7(8H)-ones as new selective orally bioavailable TTK inhibitors. All the pharmacokinetic studies were carrie
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