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    搜索結果包含 plasma 的內容

    Jul 06,2023
    Ulotaront是一種具有5-HT1A激動劑活性的TAAR1 激動劑，可用于治療精神分裂癥。Ulotaront在大鼠腦中的分布和在猴血漿中的PK研究通過尊龍凱時進行
    Ulotaront (SEP-363856) is a TAAR1 agonist with 5-HT1A agonist activity currently in clinical development for the treatment of Schizophrenia. Ulotaront exhibits rapid absorption, greater than 70% bioav
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    Jul 06,2023
    開發和驗證大鼠血漿中Nobiliside A定量的LC/MS/MS方法
    Nobiliside A, a new triterpene glycoside, exhibits some biological activities including antifungal and cytotoxic effects. A LC/MS/MS method was developed and validated for determination of Nobiliside
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    Jul 06,2023
    Columbin具有多種藥理活性，包括體內抗炎和抗腫瘤活性，此實驗中動物研究通過尊龍凱時進行
    Columbin is an important component isolated from Radix Tinosporae. Columbin possesses many pharmacological activities, including anti-inflammation, and antitumor activity in vivo. The purpose of the p
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    Jul 06,2023
    開發一種簡單準確的液相色譜串聯質譜法，用于大鼠血漿中牡荊素鼠李糖苷的測定和體內PK研究。此研究中動物研究通過尊龍凱時進行
    A simple and accurate liquid chromatography coupled with tandem mass spectrometry method was developed for determination and in vivo pharmacokinetic studies of vitexin rhamnoside in rat plasma. Practi
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    Jul 06,2023
    氯磺丙脲對蠕蟲和人肺成纖維細胞MRC-5細胞具有抗衰老作用，氯磺丙脲在小鼠中的生物利用度測定通過尊龍凱時進行
    Sulfonylureas exert their anti-diabetic effects by inhibiting K-ATP channels in the plasma membrane of islet β-cells. Chlorpropamide acts on complex II directly or indirectly via mitoK-ATP to produce
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    Jun 28,2023
    法尼基轉移酶抑制劑LNK-754單次口服后即可快速穿過血腦屏障，本研究中PK分析通過尊龍凱時進行
    Pharmacokinetic studies revealed that after a single oral dose, the FTI (LNK-754) was cleared from plasma within 20 hours and could rapidly cross the blood-brain-barrier. Pharmacokinetic analysis was performed as a service provided by Medicilon.
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    Jun 28,2023
    ARD-2128是一種PROTAC AR降解劑，具有出色的血漿和微粒體穩定性，本研究中體外穩定性和PK研究通過尊龍凱時進行
    ARD-2128 has excellent plasma and microsomal stability in all the five species (Human, Mouse, Rat, Dog, and Monkey). The in vitro stability and pharmacokinetic (PK) studies were performed by Medicilon.
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