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    搜索結果包含 model 的內容

    Jun 12,2025
    新型5-HT3受體配體有望用于治療神經精神疾病和胃腸道疾病,本研究中藥理藥效學研究通過尊龍凱時進行
    The experiments (Rat colon distension model of IBS-d) were carried out by Medicilon. The protocol complied with and was approved by the Institutional Animal Care and Use Committee and Medicilon is accredited by the NIH Office of laboratory Animal Welfare
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    Jun 11,2025
    通過聯合治療提高免疫療法療效,本研究中臨床前體內藥效研究通過尊龍凱時進行
    The flowcytometry (FCM)-based immune profiling panel studies in J558 allograft syngeneic mouse models were performed at Medicilon. In vivo efficacy studies in J558 allograft models in combination with anti-mPD-1, anti-mPD-L1, and anti-mCTLA-4 antibodies w
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    Jul 06,2023
    FBPase是與腫瘤和2型糖尿病相關的一個有前景的靶點。化合物W8對FBPase表現出高選擇性。W8的藥代動力學研究通過尊龍凱時進行
    Fructose-1,6-bisphosphatase (FBPase) is a promising target associated with cancer and type 2 diabetes. Compounds W8 and W8k exhibit high selectivity against FBPase and W8 effectively reduces blood glu
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    Jul 06,2023
    AD80是一種多激酶抑制劑,在多種肝細胞癌臨床前動物模型中具有抗腫瘤活性,AD80在血漿中的含量通過尊龍凱時進行LC-MS/MS測定
    Liver cancer is the fourth greatest cause of cancer related mortality. AD80 is a multi-kinase inhibitor with anti-tumoral activity across a variety of hepatocellular carcinoma (HCC) preclinical models
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    Jul 06,2023
    免疫檢查點阻斷療法改變了癌癥治療的范式,此研究中通過尊龍凱時在23 個同源腫瘤模型中進行了抗PD-1抗體的體內研究
    Immune checkpoint blockade therapies have changed the paradigm of cancer therapies. Reseachers performed?in vivo?screening for anti-PD-1 therapy across 23 syngeneic tumor models and found th
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    Jul 05,2023
    研究人員開發了一種高特異性的CDC7抑制劑TAK-931作為臨床腫瘤治療劑,抗腫瘤藥效研究通過尊龍凱時進行
    Cell division cycle 7 (CDC7) plays important roles in DNA replication. Researchers developed a highly specific CDC7 inhibitor, TAK-931, as a clinical cancer therapeutic agent. The antitumor efficacy s
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    Jun 28,2023
    TAK-931是一種高特異性CDC7抑制劑,具有抗腫瘤功效,本研究中體內藥效實驗通過尊龍凱時進行
    In vivo efficacy studies in J558 allograft models in combination with anti-mPD-1, anti-mPD-L1, and anti-mCTLA-4 antibodies were performed at Medicilon.
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    Jun 28,2023
    GS-5801是一種高效KDM5抑制劑,具有抗HBV活性,本研究中GS-5801通過尊龍凱時合成
    GS-5801, a potent inhibitor of KDM5, has antiviral activity against HBV in a primary human hepatocytes infection model, with the cellular permeability, oral bioavailability. GS-5801 was synthesized by Medicilon.
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    Apr 10,2017
    尊龍凱時腫瘤動物模型亮相“SAPA-DC2017年度科學研討會”
    美中藥協大華府/巴爾的摩分會(SAPA-DC)2017年度科學研討會于美國馬里蘭州Rockville圓滿落幕!會議上,尊龍凱時生物部副總裁汪俊博士發表了“Animal Models in Drug Discovery on Immunotherapy at Medicilon”主題演講。報告中,汪博士向與會者展示了尊龍凱時腫瘤動物模型的最新進展并分享了部分技術數據。
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    Nov 02,2015
    糖尿病動物模型(Animal model of diabetes melitus)
    糖尿病動物模型(Animal model of diabetes melitus)通常分誘發性和自發性兩類。
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